Selected Peer-Reviewed Publications (in chronological order)
Selker HP, Griffith JL, D'Agostino RB. A time-insensitive predictive instrument for acute mortality due to congestive heart failure: Development, testing, and use for comparing hospitals. A multicenter study. Med Care. 1994;32:1040-1052.
Udelson JE, Coleman PS, Metherall J, Pandian NG, Gomez AR, Griffith JL, Shea NL, Oates E, Konstam MA. Predicting recovery of severe regional ventricular dysfunction: Comparison of resting scintigraphy with thallium 201 and technetium 99-sestamibi. Circulation. 1994;89:2552-2561.
Maynard C, Selker HP, Beshansky JR, Griffith JL, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL, Wagner GS, Weaver WD. The exclusion of women from clinical trials of thrombolytic therapy: Implications for developing the thrombolytic predictive instrument. Med Decis Making. 1995;15:38-43.
Katz DA, Griffith JL, Beshansky JR, Selker HP. The use of empiric clinical data in the evaluation of practice guidelines for unstable angina. JAMA. 1996;276:1568-1574.
Maynard C, Beshansky JR, Griffith JL, Selker HP. The influence of sex on the use of cardiac procedures in patients presenting to the emergency department: A prospective multicenter study. Circulation. 1996;94:93-98.
Hayes DL, Wang PJ, Reynolds DW, Estes M, Griffith JL, Steffens RA, Carol GL, Findlay GK, Johnson CM. Pacemaker interference from hand-held wireless telephones: Results of a multi-center study. N Engl J Med. 1997;336:1473-73.
Sege B, Perry C, Stigol L, Cohen L, Cohn L, Griffith J, Cohen M, Spivak H. Short-term effectiveness of anticipatory guidance to reduce early childhood risks for subsequent violence. Arch Pediatr Adolesc Med. 1997;151:392-397.
Zucker DR, Griffith JL, Beshansky JR, Selker HP. Presentations of acute myocardial infarctions in men and women: Results from a prospective, multicenter study. J Gen Intern Med. 1997;12:79-87.
Selker HP, Griffith JL, Beshansky JR, Schmid CH, Califf RM, D’Agostino RB, Laks MM, Lee KL, Maynard C, Selvester RH, Wagner GS, Weaver WD. Patient-specific predictions of outcomes in myocardial infarction for real-time emergency use: a thrombolytic predictive instrument. Ann Intern Med. 1997;127:538-556.
Selker HP, Beshansky J, Griffith J, et al. The use of the Acute Cardiac Ischemic Time-Insensitive Predictive Instrument (ACI-TIPI) to assist ED triage of patients with chest pain or other symptoms suggestive of acute cardiac ischemia: a multicenter controlled clinical trial. Ann Intern Med. 1998;129:845-55.
Burns J, Mitchell C, Outwater K, Geller M, Griffith J, Todres I, Truog R. End-of-life care in the pediatric intensive care unit after the forgoing of life-sustaining treatment. Crit Care Med. 2000;28(8):3060-66.
Pope HJ, Aufderheide TP, Ruthazer R, Woolard RH, Feldman JA, Beshansky JR, Griffith JL, Selker HP. Missed diagnoses of ACI in the emergency department. N Engl J Med. 2000;342:1163-1170.
Burns JP, Mitchell C, Griffith JL, Truong RD. End-of-life care in the pediatric intensive care unit: attitudes and practices of pediatric clinical care physicians and nurses. Crit Care Med. 2001;29(3):695-696.
Moskowitz H, Griffith JL, DiScala C, Sege RD. Serious injuries and deaths of adolescent girls resulting from interpersonal violence: Characteristics and trends from the United States, 1989-1998. Arch Pediatr Adolesc Med. 2001;155:903-908.
Gill CJ, Griffith JL, Jacobson D, Skinner S, Gorbach SL, and Wilson IB. Relationship of HIV viral loads, CD4 counts, and HAART use to health-related quality of life. JAIDS. 2002;30:485-492.
Sarnak MJ, Tighiouart H, Manjunath G, MacLeod B, Griffith JL, Salem D, Levey AS. Anemia as a risk factor for cardiovascular disease in the atherosclerosis risk in communities (aric) study. J Am College Cardiol. 2002;40(1):27-33.
Selker HP, Beshansky JR, Griffith JL, For the TPI Trial Investigators. Use of the electrocardiograph-based thrombolytic predictive instrument to assist thrombolytic and reperfusion therapy for acute myocardial infarction: a multicenter randomized clinical effectiveness trial. Ann Intern Med. 2002 137:87-95.
Greenfield S, Kaplan SH, Kahn R, Ninomiya J, Griffith JL. Profiling care provided by different groups of physicians: Effects of patient case-mix (Bias) and physician-level clustering on quality assessment results. Ann Intern Med. 2002;136:111-121.
Meyer EC, Burns JP, Griffith JL, Truog RD. Parental perspectives on end-of-life care in the pediatric intensive care unit. Crit Care Med. 2002;30(1): 226-231.
Udelson JE, Beshansky JR, Ballin DS, Feldman JA, Griffith JL, Heller GV, Hendel RC, Pope JH, Ruthazer R, Spiegler EJ, Woolard RH, Handler JH, Selker HP, Myocardial Perfusion Imaging for Evaluation and Triage of Patients With Suspected Acute Cardiac Ischemia. JAMA. 2002;28(21) 2693-2700.
Selker HP, Raitt MH, Schmid CH, Laks MM, Beshansky JR, Griffith JL, Califf RM, Selvester RH, Maynard C, D'Agostino RB and Weaver WD. Time-Dependent Predictors of Primary Cardiac Arrest in Patients with Acute Myocardial Infarction. Am J Cardiol. 2003;91:280-286.
Scott TM, Tucker KL, Bhadelia A, Benjamin B, Patz S, Bhadelia R, Liebson E, Price LL, Griffith J, Rosenberg I, Folstein MF. Homocysteine and B vitamins relate to brain volume and white-matter changes in geriatric patients with psychiatric disorders. Am J Geriatr Psychiatry. 2004;12(6):631-8.
Weiner D, Tighiouart H, Stark P, Amin M, MacLeod B, Griffith J, Salem D, Levey A, Sarnak M. Kidney disease as a risk factor for recurrent cardiovascular disease and mortality. Am J Kidney Dis. 2004;44(2): 198-206.
Coronado BE, Pope JH, Griffith JL, Beshansky JR, Selker HP. Clinical features, triage, and outcome of patients presenting to the ED with suspected acute coronary syndromes but without pain: A multicenter study. Am J Emerg Med. 2004;22:568-574.
Dansinger ML, Gleason JA, Griffith JL, Selker HP, Schaefer EJ. Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial.[see comment]. JAMA. 2005;293(1):43-53.
Weiner DE, Tighiouart H, Vlagopoulos PT, Griffith JL, Salem DN, Levey AS, Sarnak MJ. Effects of anemia and left ventricular hypertrophy on cardiovascular disease in patients with chronic kidney disease. J Amer Soc Nephrol. 2005;16(6):1803-1810.
Vlagopoulos PT, Tighiouart H, Weiner DE, Griffith J, Pettitt D, Salem DN, Levey AS, Sarnak MJ. Anemia as a risk factor for cardiovascular disease and all-cause mortality in diabetes: the impact of chronic kidney disease. J Amer Soc Nephrol. 2005;16(11):3403-3410.
Golan Y, Doron S, Griffith J, El Gamal H, Tanios M, Blunt K, Barefoot L, Bloom J, Gamson K, Snydman LK, Hansjosten K, Elnekave E, Nasraway SA, Snydman DR. The impact of gown-use requirement on hand hygiene compliance. Clin Infect Dis. 2006;42(3):370-376.
Trokel M, Waddimba A, Griffith J, Sege R. Variation in the diagnosis of child abuse in severely injured infants.[erratum appears in Pediatrics. 2006 Sep;118(3):1324 Note: Wadimmba, Anthony [corrected to Waddimba, Anthony]]. Pediatrics. 117(3):722-728, 2006.
Weiner DE, Tabatabai S, Tighiouart H, Elsayed E, Bansal N, Griffith J, Salem DN, Levey AS, Sarnak MJ. Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular disease. Am J Kidney Dis. 2006;48(3):392-401.
Zalenski R, Gillum RF, Quest TE, Griffith JL. Care for the adult family members of victims of unexpected cardiac death. [Review] [63 refs] Acad Emerg Med. 2006;13(12):1333-1335.
Scott TM, Peter I, Tucker KL, Arsenault L, Bergethon P, Bhadelia R, Buell J, Collins L, Dashe JF, Griffith J, Hibberd P, Leins D, Liu T, Ordovas JM, Patz S, Price LL, Qiu WQ, Sarnak M, Selhub J, Smaldone L, Wagner C, Wang L, Weiner D, Yee J, Rosenberg I, Folstein M. The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound
elderly population. International J Geriatric Psych. 2006;21(6):519-28.
Bansal N, Tighiouart H, Weiner D, Griffith J, Vlagopoulos P, Salem D, Levin A, Sarnak MJ. Anemia as a risk factor for kidney function decline in individuals with heart failure. Am J Cardiol. 2007;99(8):1137-1142.
Weiner DE, Tighiouart H, Griffith JL, Elsayed E, Levey AS, Salem DN, Sarnak MJ. Kidney disease, Framingham risk scores, and cardiac and mortality outcomes. Am J Med. 2007;120(6):552.e1-8.
Vega-Lopez S, Ausman LM, Griffith JL, Lichtenstein AH. Interindividual variability and intra-individual reproducibility of glycemic index values for commercial white bread. Diabetes Care. 2007;30(6):1412-17.
Elsayed EF, Tighiouart H, Griffith J, Kurth T, Levey AS, Salem D, Sarnak MJ, Weiner DE. Cardiovascular disease and subsequent kidney disease.[see comment]. Arch Intern Med. 2007;167(11):1130113-6.
Weiner DE, Tighiouart H, Levey AS, Elsayed E, Griffith JL, et al. Lowest systolic blood pressure is associated with stroke in stages 3 to 4 chronic kidney disease. J Am Soc Nephrol. 2007;18(3):960-966.
Kent DM, Ruthazer R, Griffith JL, Beshansky JR, Grines CL, Aversano T, Concannon TW, Zalenski RJ, Selker HP. Comparison of mortality benefit of immediate thrombolytic therapy versus delayed primary angioplasty for acute myocardial infarction. Am J Cardiol. 2007;99(10):13841388.
Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ. The Framingham predictive instrument in chronic kidney disease. J Am Coll Cardiol. 2007;50(3):217-224.
Pereira AA, Weiner DE, Scott T, Chandra P, Bluestein R, Griffith J, Sarnak MJ. Subcortical cognitive impairment in dialysis patients. Hemodial Int. 2007;11(3):309-14.
Elsayed EF, Sarnak MJ, Tighiouart H, Griffith JL, Kurth T, Salem DN, Levey AS, Weiner DE. Waist-to-hip ratio, body mass index, and subsequent kidney disease and death. Am J Kidney Dis. 2008;52(1):29-38.
Elsayed EF, Tighiouart H, Weiner DE, Griffith JL, Salem D, Levey AS, Sarnak MJ. Waist-to-hip ratio and body mass index as risk factors for cardiovascular events in CKD. Am J Kidney Dis. 2008;52(1):49-57.
Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ. Inflammation and cardiovascular events in individuals with and without chronic kidney disease.[see comment]. Kidney Int. 2008;73(12):1406-12.
Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS. Uric acid and incident kidney disease in the community. J Am Soc Nephrol. 2008;19(6):1204-11.
Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, et al. The relationship between nontraditional risk factors and outcomes in individuals with stage 3 to 4 CKD. Am J Kidney Dis. 2008;51(2):212-23.
Concannon TW, Kent DM, Normand SL, Newhouse JP, Griffith JL, Ruthazer R, Beshansky JR, Wong JB, Aversano T, Selker HP. A geospatial analysis of emergency transport and inter-hospital transfer in ST-segment elevation myocardial infarction. Am J Cardiol. 2008;101(1):69-74.
Kent DM, Ruthazer R, Griffith JL, Beshansky JR, Concannon TW, Aversano T, Grines CL, Zalenski RJ, Selker HP. A percutaneous coronary intervention-thrombolytic predictive instrument to assist choosing between immediate thrombolytic therapy versus delayed primary percutaneous coronary intervention for acute myocardial infarction. Am J Cardiol. 2008;101(6):790-5.
Lai CQ, Tucker KL, Parnell LD, Adiconis X, Garcia-Bailo B, Griffith J, Meydani M, Ordovas JM. PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study. Diabetes. 2008;57(4):809-16.
Flaherty EG, Sege RD, Griffith J, Price LL, Wasserman R, Slora E, Dhepyasuwan N, Harris D, Norton D, Angelilli ML, Abney D, Binns HJ. From suspicion of physical child abuse to reporting: primary care clinician decision-making.[see comment]. PROS network. NMAPedsNet. Pediatrics. 2008;122(3):611-9.
Layne JE, Sampson SE, Mallio CJ, Hibberd PL, Griffith JL, Das SK, Flanagan WJ, Castaneda-Sceppa C. Successful dissemination of a community-based strength training program for older adults by peer and professional leaders: the people exercising program. J Am Geriatrics Soc. 2008;56(12):2323-9.
Madan J, Fiascone J, Balasubramanian V, Griffith J, Hagadorn JI. Predictors of ductal closure and intestinal complications in very low birth weight infants treated with indomethacin. Neonatology. 2008;94(1):45-51.
Weiner DE, Bartolomei K, Scott T, Price LL, Griffith JL, Rosenberg I, Levey AS, Folstein MF, Sarnak MJ.
Albuminuria, cognitive functioning, and white matter hyperintensities in homebound elders. Am J Kidney Dis. 2009;53(3):438-47.
Kaplan SH, Griffith JL, Price LL, Pawlson LG, Greenfield S. Improving the reliability of physician performance assessment: identifying the "physician effect" on quality and creating composite measures.[see comment]. Med Care. 2009;47(4):378-87.
Active Research Support/Grants
U01 HL 077826 (D’Agostino)
9/1/04- 8/31/09
NHLBI
Data Coordinating Center: The IMMEDIATE Trial
This application is one of four grant applications that together support the conduct of the IMMEDIATE Trial. The Data Coordinating Center handles all data on the trial and is responsible for the analysis.
R01 DK080112 (Sarnak)
4/1/08-3/31/11
NIH/NIDDK
Cognition and Dialysis.
This study investigates the range and change in cognitive measures in incident and prevalent hemodialysis patients.
UL1 RR 025752 (Selker)
5/19/08-4/30/13
NIH/NCRR
Tufts Clinical and Translational Science Institute
This Clinical and Translational Science Award supports and instills the culture of cooperative interdisciplinary research by creating a new home for clinical and translational research across the University and clinical affiliates.
R01 NS 062153 (Kent)
12/1/08-11/30/12
NIH/NINDS
The Risk of Paradoxical Embolism (RoPE) Study
This project aims to examine the largest collection of patients ever assembled from databases worldwide to determine which stroke patients with a patent foramen ovale (PFO) should have their PFO endovascularly closed in order to prevent another stroke and to identify those for whom PFO-closure would not be likely to help and may even lead to harm.