Dr. Selker is Executive Director for the Institute for Clinical Research and Health Policy Studies, Chief of the Division of Clinical Care Research, Director of the Center for Cardiovascular Health Services Research at Tufts Medical Center and Dean, Tufts Clinical and Translational Science Institute. He is also Professor of Medicine at Tufts University School of Medicine and Director of its Graduate Program in Clinical Research at the Tufts Sackler School of Graduate Biomedical Sciences. His clinical practice is in the Pratt Diagnostic Center at Tufts Medical Center. In his research, Dr. Selker studies the factors that affect clinical care and its outcomes, and develops treatment strategies, decision aids, and computer-based systems for improving care. He is known for a series of studies of the factors influencing emergency cardiac care, including clinical, socioeconomic and gender issues, and is particularly known for the development of cardiac "clinical predictive instruments." These decision aids provide emergency physicians with predictions of their patients' key outcomes for real-time use in clinical care. Two of these, the ACI-TIPI (acute cardiac ischemia time-insensitive predictive instrument) and TPI (thrombolytic predictive instrument), are in electrocardiographs in use world-wide. He also is known for the development of information systems that provide the results of the ACI-TIPI and TPI as feedback to improve clinical care. In addition, Dr. Selker's research includes work on fundamental issues of clinical study design, data analysis, combination of clinical data, and computer-based mathematical models that predict clinical outcomes.
Dr. Selker is also an active teacher and mentor of clinical researchers. His was the first of its kind MS/PhD graduate program in clinical research in a biomedical graduate school, and he has been involved nationally in the promotion of clinical research and clinical research training. He holds leadership roles in professional and scientific societies and serves on a variety of governmental and organizational committees and panels.
